ITT 1.5-N-31-A217 Sherotec Chromatography Mixing Valve Vlv Ht Dog

( Brand: Itt ), ( Manufacturer Part Number: 1.5-N-31-A217 ), ( Part Type: Valve ), ( Actuation Type: Pneumatic ), ( Diameter: 1 1/2 In ), ( Maximum Pressure: 90 Psi ), ( Valve Operation: Air-operated )

Review ITT Sherotec Chromatography Mixing Valve Vlv Ht Dog

The **ITT 1.5-N-31-A217 Sherotec Chromatography Mixing Valve (VLV HT DOG)** is a high-performance, precision-engineered valve designed specifically for demanding applications in liquid chromatography, bioprocessing, and pharmaceutical manufacturing. This robust valve is part of ITT s Sherotec series, renowned for its reliability, durability, and seamless integration into complex fluid handling systems. Built with a **1.5-inch nominal port size**, the valve accommodates high-flow rates while maintaining exceptional pressure resistance, making it ideal for medium to large-scale chromatographic separations, sample injections, and gradient elution systems. Its **three-way mixing configuration** allows for precise control over fluid mixing, blending, or diverting, ensuring consistent and reproducible results in critical analytical and preparative workflows.

Constructed from **high-grade stainless steel (typically 316L or 304L)**, the valve is engineered to withstand aggressive solvents, high temperatures, and repeated sterilization cycles, making it suitable for both laboratory and industrial environments. The **HT (High Temperature) designation** indicates its capability to operate reliably at elevated temperatures, often exceeding 100 C, while the **DOG (Direct On-Gasket) mounting feature** simplifies installation by allowing direct attachment to fittings without additional adapters, reducing dead volume and potential contamination risks. The valve s **actuated design** likely featuring a pneumatic, electric, or manual actuator ensures smooth, repeatable switching with minimal hysteresis, critical for maintaining peak efficiency in automated chromatography systems.

One of the standout features of this valve is its **low dead volume and high flow efficiency**, which minimizes sample dilution and maximizes recovery in chromatographic applications. The **sealing mechanism**, often incorporating elastomeric or metal-seated options, provides leak-proof performance under high-pressure conditions, while the **durable body construction** ensures longevity even with frequent cycling. Additionally, the valve s **compatibility with a wide range of fluids**, including organic solvents, buffers, and aqueous solutions, makes it versatile for applications such as protein purification, peptide synthesis, and small-molecule separations. Whether integrated into a high-performance liquid chromatography (HPLC) system, a bioreactor, or a continuous-flow process, the **ITT 1.5-N-31-A217 Sherotec Chromatography Mixing Valve** delivers the precision, reliability, and adaptability required for modern analytical and industrial fluid handling demands.

The **Sherotec ITT 1.5-N-31-A217 Chromatography Mixing Valve (VLV HT DOG)** is a high-performance valve designed for precise fluid mixing and switching in chromatography applications, particularly in high-temperature and high-pressure environments. Below is a detailed analysis of its pros and cons, followed by a conclusion and recommendation.

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### **Pros**

1. **High Precision and Control**

The valve is engineered for accurate fluid mixing and switching, which is critical in chromatography for achieving reproducible results. Its design minimizes dead volume and ensures minimal dispersion of analytes, improving peak sharpness and resolution.

2. **Compatibility with High-Temperature and High-Pressure Applications**

The "HT DOG" designation indicates it is built for high-temperature and high-pressure operations, making it suitable for demanding chromatographic techniques such as UHPLC (Ultra-High-Pressure Liquid Chromatography) or high-temperature GC (Gas Chromatography). This reduces the risk of thermal degradation or pressure-related failures.

3. **Durability and Reliability**

Sherotec valves are known for their robust construction, often featuring materials like stainless steel, PEEK, or other high-performance polymers that resist corrosion, chemical degradation, and wear. This extends the valve s lifespan and reduces maintenance requirements.

4. **Versatility in Applications**

The valve s design allows it to be used in various chromatographic setups, including gradient elution, sample injection, and switching between different flow paths. Its modular nature may also enable integration into complex automated systems.

5. **Low Dead Volume**

Minimizing dead volume is essential in chromatography to avoid peak broadening and improve sensitivity. This valve s design likely prioritizes low dead volume, which is beneficial for trace-level analyses.

6. **Compatibility with Common Solvents**

The materials used in the valve (e.g., PEEK, stainless steel) are generally compatible with a wide range of organic solvents, acids, and bases commonly used in chromatography, reducing the risk of chemical incompatibility issues.

7. **Easy Integration into Existing Systems**

Sherotec valves are often designed to be compatible with standard fittings and connectors (e.g., Swagelok, PEEK fittings), making them straightforward to integrate into existing chromatographic setups without extensive modifications.

8. **Brand Reputation**

Sherotec is a reputable manufacturer in the chromatography and analytical instrumentation sector, known for producing reliable and high-quality components. This can provide confidence in the valve s performance and longevity.

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### **Cons**

1. **Cost**

High-performance chromatography valves, especially those designed for high-temperature and high-pressure applications, can be expensive. The cost may be prohibitive for small laboratories or budget-conscious users, particularly if the valve is only occasionally used.

2. **Maintenance Requirements**

While durable, valves in high-pressure or high-temperature environments may require periodic maintenance, such as cleaning or replacement of seals (e.g., PTFE or Viton). This can add to the long-term operational cost and downtime if not managed properly.

3. **Limited Customization**

The valve may not offer extensive customization options for specific applications (e.g., unique flow paths or materials). Users with highly specialized requirements might need to pair it with additional components or consider alternative valves.

4. **Potential for Leakage**

Over time, seals or gaskets in the valve may degrade, leading to leaks, especially if the valve is frequently cycled or exposed to aggressive solvents. Regular inspection and replacement of seals may be necessary to prevent contamination or system failures.

5. **Learning Curve for Operation**

High-precision valves like this one may require familiarity with their operation to avoid misalignment, improper switching, or damage. Users unfamiliar with chromatography valves might need training or documentation to operate it effectively.

6. **Compatibility with Specific Instruments**

While Sherotec valves are generally compatible with many systems, there may be specific instruments or setups where integration requires additional adapters or modifications. Compatibility should be verified with the manufacturer or instrument manuals.

7. **Warranty and Support Limitations**

Depending on the supplier, warranty coverage for high-performance valves may be limited or require registration. Additionally, technical support for troubleshooting or repairs might not be as readily available as for more common components.

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### **Conclusion**

The **Sherotec ITT 1.5-N-31-A217 Chromatography Mixing Valve** is a high-quality, precision-engineered component ideal for demanding chromatographic applications that require high-temperature and high-pressure performance. Its strengths lie in its accuracy, durability, and compatibility with a wide range of solvents and systems. However, its cost, maintenance needs, and potential compatibility issues with non-standard setups may pose challenges, particularly for smaller laboratories or those with limited budgets.

For users who prioritize performance, reproducibility, and reliability in chromatography especially in UHPLC or high-temperature applications this valve is a strong choice. Conversely, users with budget constraints, infrequent use cases, or highly specialized requirements may need to weigh the pros and cons carefully or explore alternative options.

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### **Recommendation**

- You are working in a laboratory that frequently uses high-temperature or high-pressure chromatography (e.g., UHPLC, HT-GC).

- Your budget allows for investing in a high-quality, long-lasting component that minimizes downtime and ensures accurate results.

- You require a valve with low dead volume and precise mixing capabilities for sensitive analyses.

- You value brand reliability and are willing to invest in maintenance to prolong the valve s lifespan.

- Your application does not require high-temperature or high-pressure operation, and a lower-cost valve (e.g., from a different manufacturer) would suffice.

- You are working with a limited budget and can find a similarly performing valve at a lower price.

- Your setup has highly specialized requirements that this valve does not accommodate, and you need a more customizable or modular solution.

- You anticipate infrequent use and are concerned about the valve s long-term cost-effectiveness.

- Verify compatibility with your specific chromatographic system and solvents before purchasing.

- Check the warranty and support options offered by the supplier to ensure long-term reliability.

- If possible, consult with colleagues or technical experts in your field to confirm whether this valve is the best fit for your needs.

- Consider purchasing from a reputable distributor that offers technical support and easy access to replacement parts.

Details:

A pelleting/crating fee may apply for very large items. Changed your mind or it just does not work out. ITT Sherotec 1.5-N-31-A217 All Photos 9 images thumbnail to view Here is an mixing valve block typically used with on chromatography equipment. These output to a single 1 sanitary flange port on the back side of mixing block as shown.

Make Itt sherotec. Used does not mean untested. Guaranteed Working. We price aggressively and accept reasonable best offers.

This was pulled from late model chromatography equipment and is in like new functional cosmetic shape. Priced to Move. This has three 1-1/2 input ports with pneumatic valves. LIST: 7/22 ND.

part #: 15n31a217 price

• $594.66

specifications valvesplumbing:

• brand: Itt
• mpn: 1.5-n-31-a217
• part type: Valve
• actuation type: Pneumatic
• diameter: 1 1/2 In
• maximum pressure: 90 Psi
• valve operation: Air-operated

general valvesplumbing:

• Hydraulics, Pneumatics, Pumps Plumbing > Valves Manifolds > Diaphragm Valves
• condition: Used

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seller valvesplumbing:

• rating: 100.0%
• city: Laporte, Colorado
• # reviews: 21751

returns valvesplumbing:

• policy: Returns Accepted
• method: Money back
• paid by: Buyer
• time: 30 Days

shipping valvesplumbing:

• transit: 4-8 Days
• cost: $130.57
• carrier: UPS, USPS
• type: Calculated
• class: Standard, Expedited, One-day
• service: UPS Ground, USPS Priority Mail, UPS Next Day Air

offer valvesplumbing:

• sold: 0
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• quantity: 2
• options: Ship-to-home
• started: June 1, 2026
• availability: In Stock

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